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Title: Preliminary studies on plasmodium falciparum adenosine 5'monophosphate deaminase
Authors: Balaram, Hemalatha
Lakshmeesha, K.N.
Keywords: Plasmodium falciparum
Issue Date: 2014
Publisher: Jawaharlal Nehru Centre for Advanced Scientific Research
Citation: Lakshmeesha, K. N. 2014, Preliminary studies on plasmodium falciparum adenosine 5'monophosphate deaminase, MS thesis, Jawaharlal Nehru Centre for Advanced Scientific Research, Bengaluru
Abstract: "The current study focuses on the preliminary characterisation of a purine nucleotide cycle enzyme, AMP deaminase (AMPD hereafter) from Plasmodium falciparum. Purine nucleotide cycle performs inter-conversion of IMP and AMP with the release of fumarate and ammonia as by-products, which also have physiological consequences. The pathway plays a chief role in maintaining adenylate energy charge ratio, which is critical for cell survival. Cloning, expression and preliminary characterization of the enzyme has been reported in this thesis."
Appears in Collections:Student Theses (MBGU)

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