Please use this identifier to cite or link to this item: http://lib.jncasr.ac.in:8080/jspui/handle/10572/2307
Title: Cyclization and unsaturation rather than isomerisation of side chains govern the selective antibacterial activity of cationic-amphiphilic polymers
Authors: Uppu, D. S. S. M.
Bhowmik, M.
Samaddar, S.
Haldar, Jayanta
Keywords: Chemistry
Antimicrobial Peptides
Copolymers
Potent
Agents
Issue Date: 2016
Publisher: Royal Society of Chemistry
Citation: Uppu, Dssm; Bhowmik, M.; Samaddar, S.; Haldar, J., Cyclization and unsaturation rather than isomerisation of side chains govern the selective antibacterial activity of cationic-amphiphilic polymers. Chemical Communications 2016, 52 (25), 4644-4647 http://dx.doi.org/10.1039/c5cc09930g
Chemical Communications
52
25
Abstract: Membrane-active agents represent a promising alternative to overcome antibiotic resistance. Here, we report cationic-amphiphilic polymers with variations in the side chain architecture such as cyclization, isomerization and unsaturation that resulted in potent antibacterial activity and low mammalian cell toxicity with a membrane-active mode of action.
Description: Open Access (Accepted Manuscript); Restricted Access (Publisher's PDF)
URI: http://hdl.handle.net/10572/2307
ISSN: 1359-7345
Appears in Collections:Research Papers (Jayanta Haldar)

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