Please use this identifier to cite or link to this item: http://lib.jncasr.ac.in:8080/jspui/handle/10572/2014
Title: Selective and broad spectrum amphiphilic small molecules to combat bacterial resistance and eradicate biofilms
Authors: Hoque, Jiaul
Konai, Mohini M.
Samaddar, Sandip
Gonuguntala, Spandhana
Manjunath, Goutham B.
Ghosh, Chandradhish
Haldar, Jayanta
Keywords: Chemistry
Pseudomonas-Aeruginosa
Antibacterial Peptides
Persistent Infections
Peptoid Mimics
Membrane
Lipopeptides
Mechanism
Potent
Oligomers
Polymers
Issue Date: 2015
Publisher: Royal Society of Chemistry
Citation: Chemical Communications
51
71
Hoque, J.; Konai, M. M.; Samaddar, S.; Gonuguntala, S.; Manjunath, G. B.; Ghosh, C.; Haldar, J., Selective and broad spectrum amphiphilic small molecules to combat bacterial resistance and eradicate biofilms. Chemical Communications 2015, 51 (71), 13670-13673.
Abstract: Rationally designed amphiphilic small molecules selectively kill drug-sensitive and drug-resistant bacteria over mammalian cells. The small molecules disperse preformed biofilms and reduce viable bacterial count in the biofilms. Moreover, this class of membran-active molecules disarms the development of bacterial resistance.
Description: Restricted access
URI: http://hdl.handle.net/10572/2014
ISSN: 1359-7345
Appears in Collections:Research Papers (Jayanta Haldar)

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