Please use this identifier to cite or link to this item: http://lib.jncasr.ac.in:8080/jspui/handle/10572/1935
Title: A switch-on near-infrared fluorescence-ready probe for Cu(I): live cell imaging
Authors: Maity, Debabrata
Raj, Anand
Karthigeyan, D.
Kundu, Tapas Kumar
Govindaraju, T.
Keywords: Chemistry
fluorescence-ready probe
near-infrared emission
copper(I)
C-O bond cleavage
live cell imaging
Living Cells
Nir Fluorescence
Cu-II
Copper
Sensor
Ions
Recognition
Diseases
Cobalt
Dyes
Issue Date: 2015
Publisher: Taylor & Francis Ltd
Citation: Supramolecular Chemistry
27
9
Maity, D.; Raj, A.; Karthigeyan, D.; Kundu, T. K.; Govindaraju, T., A switch-on near-infrared fluorescence-ready probe for Cu(I): live cell imaging. Supramolecular Chemistry 2015, 27 (9), 589-594.
Abstract: A reaction-based strategy exploiting metal ion mediated oxidative C-O bond cleavage affords selective switch-on' near-infrared (NIR) emitting cyanine probe for Cu+ in aqueous media and live cells. Near-infrared fluorescence-ready probe TPACy readily reacts with Cu+ to release the quinone embedded heptamethine cyanine (Cy-quinone) with extended -electron conjugation responsible for the switch-on NIR fluorescence in aqueous buffer solution (50mM HEPES, pH 7.2). This probe can be conveniently used for monitoring Cu+ without the interference from pH dependent effects of physiological media. Utility of the probe has been demonstrated by its application in the detection of unbound copper species (Cu+) in live cells.
Description: Restricted access
URI: http://hdl.handle.net/10572/1935
ISSN: 1061-0278
Appears in Collections:Research Papers (Tapas K. Kundu)

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