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|Title:||Revealing the trehalose mediated inhibition of protein aggregation through lysozyme-silver nanoparticle interaction|
|Publisher:||Royal Society of Chemistry|
Siddhanta, S.; Barman, I.; Narayana, C., Revealing the trehalose mediated inhibition of protein aggregation through lysozyme-silver nanoparticle interaction. Soft Matter 2015, 11 (37), 7241-7249.
|Abstract:||We propose a facile and robust carbohydrate-mediated method for the prevention of nanoparticle induced denaturation and aggregation of proteins. Using label-free plasmon-enhanced Raman spectroscopy measurements, the mechanistic principles of trehalose stabilization in a model protein-nanoparticle system are elucidated for the first time, facilitating its further application in diagnostic and therapeutic nanoplex development.|
|Appears in Collections:||Research Articles (Chandrabhas N.)|
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